Ionis Pharmaceuticals (NASDAQ: IONS)

by | Sep 3, 2025 | Daily Trade Alerts

Ionis Pharmaceuticals (NASDAQ: IONS) – Biotech Breakout from the Shadows


Why Watch It Tomorrow

Ionis just surged into the elite technical tier—its Relative Strength (RS) Rating climbed from 81 to 94, signaling one of the strongest performers across the market. That’s about as rare as it gets for biotech names and often hints at serious upside potential.


Most importantly, IONS has broken out of a second-stage cup-with-handle base, clearing the buy point at $48.61 and entering an extended trajectory. While it’s currently outside the ideal entry range, the stock could reset soon with tighter setups like a three-weeks tight formation or a retracement to key support levels.


Fundamentally, while earnings were flat, revenues doubled (+101%), showcasing robust demand for its pipeline-stage therapies.


Key Drivers Table

CatalystInsight
Elite RS Rating (94)Reflects standout performance compared to market peers—often precedes breakout runs.
Breakout ConfirmedCleared the cup-with-handle buy point of $48.61—textbook technical signal.
Massive Sales Growth+101% revenue lift shows underlying momentum—especially notable in biotech.
Setup Still AliveExtended? Yes—but a tightening pattern or pullback could offer a second chance to enter.


Final Take

Ionis Pharmaceuticals is flashing deep technical strength: an elite RS rating, breakout from a reliable base, and blockbuster revenue growth. If you’re looking for high-upside biotech setups, IONS deserves a place on your radar. Watch for a potential pullback or tight consolidation for an optimal entry.

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